College of Liberal Arts & Sciences

Simulations of LeuT and DAT Transporters

Jan 29, Tue 2007
11:00 am, MRB 200 Conference Room

Dr. Jeffry Madura

Duquesne University

The nature of the physical and chemical properties of proteins and transporters, e.g. dopamine transporter, and their role has challenged experimental and computational scientists for several decades. Experimental data has shed some light into the macroscopic properties of these proteins while molecular simulations have provided some molecular insight. In this talk I will focus on the comparative modeling of the dopamine transporter as well as the results from docking calculations of dopamine, amphetamine, benztropine and cocaine.


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