On the Force Dependence of Biomolecular Conformational Kinetics
May 1, Tue 2007
11:00am, MRB Conference Room
University of Michigan
Two aspects concerning the effect of external forces on biomolecular conformational kinetics will be presented. Firstly, we shall address the structural transitions, thermodynamic equlibrium and the phase diagram of DNA and RNA under torque and tension. Secondly, we shall present a stochastic path integral formalism enabling the calculation of the force dependence of the kinetic rate constant for conformational transitions.